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Endometrial Scratch Appears Beneficial in Couples Trying to Conceive

There is a much disputed claim that “injury” to the lining of the uterus — whether inadvertent or deliberate — increases the chance of embryo implantation and thus the chance of pregnancy in certain groups of women having IVF. The “injury” has usually been performed as a biopsy from the womb lining (endometrium), whose action is believed to cause a favourable inflammation (“scratch”) within the endometrium thereby making it more receptive to an implanting embryo. Indeed, the success of more complex uterine surgery in some studies has even been attributed to the scratch and not to the surgery itself.

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