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New Nanoparticle Chemo Is Gentler On Fertility

RestingEggFolliclesUsing nanoparticles as “Trojan horses”, scientists have designed and lab-tested a way to deliver an arsenic-based chemo drug that ferociously attacks cancer, but is gentler on the ovaries. They hope the new method will help to protect the fertility of women undergoing cancer treatment.

The team also developed a rapid way to test existing and new chemo drugs for their effect on ovarian function, so doctors and their female patients can make treatment decisions that minimize damage to ovaries and thus increase the chance of having a future family.

The new nanoparticle chemo drug they designed is the first cancer drug to be tested while in development for its effect on fertility using the new rapid toxicity test.

Advances in cancer therapy means more patients are surviving, but many female patients often face a temporary or permanent loss of fertility after undergoing traditional chemotherapy. Read full article.

Fertility Clock Headlines, Fertility Headlines

UK Surgeons Launch Womb Transplant Charity

A charity has been launched to raise money for research that could allow the first womb transplants in the UK.

Uterine Transplantation UK was set up by a team of British surgeons who say they need £500,000 to finish testing the procedure. Only after tests in animals have been completed will they be able to apply for ethics permission to perform the surgery in patients.

Womb transplantation offers an alternative to surrogacy or adoption for thousands of women who are either born without a womb or have theirs removed due to birthing complications, cancer or other diseases.

A previous attempt at this surgery in 2000 failed because of a problem in the blood supply to the transplanted uterus. However, several improvements to the technique have been made and last August a 21-year old woman in Turkey became the first successful recipient of a womb transplant.

‘We are confident, especially with a transplant abroad being carried out with the same methodology that we have recommended that within two years or so, given enough funding, we can begin helping women in the UK’, said Mr Richard Smith, a consultant gynaecologist from Imperial College Healthcare NHS Trust and the Lister Hospital.

Read full article.