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Why Do We Inherit Mitochondrial DNA Only From Our Mothers?

Our mitochondrial DNA accounts for a small portion of our total DNA. It contains just 37 of the 20,000 to 25,000 protein-coding genes in our body. But it is notably distinct from DNA in the nucleus. Unlike nuclear DNA, which comes from both parents, mitochondrial DNA comes only from the mother. Nobody fully understands why or how fathers’ mitochondrial DNA gets wiped from cells. An international team of scientists recently studied mitochondria in the sperm of a roundworm called C. elegans to find answers.

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Fertility Treatment Not Tied to Twin Birth Defects

Twins born after fertility treatments may be susceptible to different — and fewer — birth defects than other twins, new research suggests. The study confirms that twins have a higher risk of birth defects than singletons, but it questions the notion that fertility treatments contribute to those abnormalities.

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Bioethics in China: No Wild East

The first and only published papers to describe genome modification in human embryos have come from Chinese laboratories. For some, this is another signal of China’s successful transformation from a closed society focused on farming and the manufacturing of commodities to a world leader in innovation. For others, these studies are the latest in a list of feats reported over the past decade that reflect the country’s lax regulation or cultural indifference to fundamental ethical tensions.

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Do Women Who Donate Their Eggs Run a Health Risk?

Maggie Eastman considers it the worst decision she ever made. In 2003, beset by $30,000 in tuition debt and imbued with a burst of altruism, Eastman, a college senior, decided to donate her eggs to help an infertile couple have a baby. Over the next decade she donated nine more times, earning a total of about $20,000 — money that helped Eastman and her then-husband buy a house.

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These Feminine Smells Get Sperm Moving

Sperm are the cheetahs of the microscopic world: Made of little more than molecular muscle and batteries, tipped with a payload of genetic information, they are optimized for speed. But to orient themselves before their epic, seven-inch sprint (it’s more impressive if you’re less than one three-thousandth that size), they first need to sniff out the location of the egg—and, it turns out, the analogy to the sense of smell may be particularly apt.