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HPV infections return at menopause in women of sexual revolution

Signs of the cancer-causing human papilloma virus in women near or at menopause may be a reawakened dormant infection, suggesting a risk for women who came of age in the “sexual revolution” in the 1960s and 70s.

About 77 percent of the infections were detected in women who reported five or more sexual partners in their lifetime, according to a study in the Journal of Infectious Diseases. The findings released today suggest that reactivation of the sexually transmitted virus may increase around age 50 and be responsible for more later-life infections than new ones, researchers said.

The data raises a new concern for women now entering menopause, suggesting a significantly higher risk for HPV infections than those of the previous generation, researchers said. The findings may mean that women need to continue routine screening after age 40, said Patti Gravitt, one of the study authors.

“If we confirm this, we may want to re-evaluate our screening strategies and confirm they’re sufficient,” said Gravitt, an associate professor at the Johns Hopkins Bloomberg School of Public Health, in a telephone interview. “If populations change their sexual behaviors, that will contribute to how we see age-specific HPV prevalence.”

HPV is found in about a quarter of teenage girls and about half of women 20 to 24, according to a 2007 study in the Journal of the American Medical Association. There isn’t a good test for men. Previous studies have found that the virus isn’t detected in samples after about two years. Read full article.

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‘Hidden’ HPV May Reactivate in Older Women, Study Suggests

(HealthDay News) — Many older women infected with the human papillomavirus (HPV) in their youth may not “clear” it from the body as completely as once thought, a new study suggests.

The research hints that HPV infection in older women is often the reactivation of a strain picked up years ago, rather than a newly acquired sexually transmitted infection.

The study authors also found that HPV may be difficult to detect in the body more than one to two years after the initial infection.

“Women who fail to ‘clear’ [HPV] infections are known to be at high risk for cervical cancer, but what are the true long-term risks for the vast majority of women who appear to clear their initial infection? The current study addresses what does ‘clearance’ really mean,” said Dr. Rhoda Sperling, professor of obstetrics, gynecology and reproductive science at the Mount Sinai School of Medicine in New York City. She was not connected to the new study. Read full article.