In the most severe form of male infertility, men do not make any measurable levels of sperm. This condition, called azoospermia, affects approximately 1 percent of the male population and is responsible for about a sixth of cases of male infertility.
Oftentimes men with azoospermia don’t know the underlying cause of their condition. But new research led by University of Pennsylvania scientists suggests that mutations in an X chromosome gene called TEX11 are responsible for a significant number of cases of infertility—an estimated 1 percent of cases of non-obstructive azoospermia.
Team Identifies Gene Responsible for Some Cases of Male Infertility
