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For Menopausal Women, Obesity Can Increase Cancer Risk

Thanksgiving dinner has turkey and cranberry sauce along with pumpkin pie. Christmas rings in the end of the year with egg nog and ginger bread cookies. During the holiday season, it can be difficult to resist these delicious treats. However, a new study shows that it may be better to avoid these tempting dishes and strike out on a more nutritious diet, particularly if you happen to be a middle-aged woman.

Researchers from the University of Colorado Cancer Center recently revealed that maintaining a healthy lifestyle during menopause could help reduce the risk of breast cancer later on.

To begin, females who are obese and postmenopausal have a greater risk of later developing breast cancer. They also found that the cancer that these women get can be more aggressive than for their healthier counterparts. The findings of the study were recently featured in the journal Cancer Research.

The team of investigators was interested in exploring ways of limiting the risk for breast cancer.

“By using nutrient tracers for fat and sugar, we tracked where the body stored excess calories. In lean models, excess fat and glucose were taken up by the liver, mammary and skeletal tissues. In obese models, excess fat and glucose were taken up by tumors, fueling their growth,” explained the study’s lead author Erin Giles, a postdoctoral researcher at the Cancer Center, in a prepared statement. Read full article.

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After Cancer, Stem Cells Restore Male Fertility

U. PITTSBURGH (US) — After an injection of banked sperm-producing stem cells, male primates who become sterile due to cancer drug side effects were once again fertile.

A study published in Cell Stem Cell, describes how previously frozen stem cells restored production of sperm that was able to successfully fertilize eggs to produce early embryos.

Some cancer drugs work by destroying rapidly dividing cells. Since it isn’t possible to discriminate between cancer cells and other rapidly dividing cells in the body, the precursor cells involved in making sperm can be inadvertently wiped out leaving the patient infertile, explains senior investigator Kyle Orwig, associate professor in the department of obstetrics, gynecology and reproductive medicine at the University of Pittsburgh School of Medicine, and an investigator at Magee-Womens Research Institute. Read full article.

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Smoking Pot Linked to Testicular Cancer Risk

Smoking marijuana may increase young men’s risk of testicular cancer, a new study suggests.

In the study, marijuana users were about twice as likely to be diagnosed with testicular cancer compared to those who had never used marijuana. The link was particularly strong for the types of testicular cancer that tend to have a worse prognosis, the researchers said. Read full article.

 

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Use of Any Type of Hormones for Menopause Symptoms Raises Breast Cancer Risk, Study Suggests

It is already known that taking pills that combine estrogen and progestin — the most common type of hormone therapy — can increase breast cancer risk. But women who no longer have a uterus can take estrogen alone, which was thought to be safe and possibly even slightly beneficial in terms of cancer risk.