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FAQ: Are Compounded Bioidentical Hormones Safe for HRT?

An analysis of two large surveys published in February in Menopause, the journal of the North American Menopause Society, reported that 28% to 68% of women using hormones at menopause take compounded, so-called “bioidentical” hormones. The analysis further revealed that women do not understand that compounded hormone products, which are not clinically tested or approved by the US Food and Drug Administration (FDA), carry innate risks.

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What’s the Latest on Hormone Replacement for Prevention?

Hormone replacement therapy (HRT) is the use of estrogen alone (for women who have had a hysterectomy) or combined with progestin (for women with an intact uterus). It is primarily used in menopausal women for relief of symptoms, particularly hot flashes. For many years, providers recommended that women continue to take HRT after menopause to prevent chronic conditions such as heart disease.

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Hormone Replacement Therapy: Navigating the Debate

Treatment options for menopause have been a minefield for many women since the publication of a landmark study in 2002 that warned about potentially negative side-effects of hormone replacement therapy (HRT). It was developed to treat hot flashes, night sweats, insomnia, vaginal dryness and other unpleasant symptoms of menopause.